Breathe Better,
Sleep Better,
Feel Better

Trust your care to fellowship-trained,
American Board of Allergy and Immunology
certified providers.

Breathe Better,
Sleep Better,
Feel Better

Trust your care to fellowship-trained,
American Board of Allergy and Immunology
certified providers.

WHAT WE dO

We treat a broad range of Allergic Diseases, Asthma and Issues involving the immune system. Please click the button to learn more.

WHAT WE tREAT

FOOD ALLERGIES

ASTHMA

ENVIRONMENTAL ALLERGIES

POLLEN / ANIMALS / DUST / MOLD SKIN TESTING

IMMUNE DISORDERS

ALLERGIC SKIN DISORDERS

SINUS DISORDERS

HIVES/ANGIOEDEMA

MAST CELL DISEASES

HOW WE TREAT

IMMUNOTHERAPY

RUSH IMMUNOTHERAPY

RAPID aLLERGIC RHINITIS DESENSITIZATION

BIOLOGICS

CONVENTIONAL & RAPID RUSH DESENSITIZATIONS

SUBLINGUAL IMMUNOTHERAPY

Environmental Allergies

IMMUNE REPLACEMENT THERAPY

FOOD SLIT (SUBLINGUAL DROPS)

ORAL IMMUNOTHERAPY DESENSITIZATION (OIT)

FOR LIFE THREATENING FOOD ALLERGIES

MEET OUR PROVIDERS

Rene Leon, MD

Dr. Rene Leon has practiced at Texas Regional Asthma, Allergy & Immunology since 1995, gaining extensive clinical experience across the spectrum of allergic and immune system disorders.

Ali Shakouri, MD

Dr. Shakouri grew up in DFW and attended Southern Methodist University, graduating Summa Cum Laude in 2002 with a degree in biological sciences with academic distinction.

Ernesto Ruiz-Huidobro, MD

Dr. Ernesto Ruiz-Huidobro is an allergist-immunologist in Southlake, Texas, who earned his medical degree from Cayetano Heredia University and has practiced over 20 years in practice.

Jesse Astorga, MPAS, PA-C

Jesse Astorga is a board-certified Physician Assistant who joined the Center in 2025 after a Master of Physician Assistant Studies from LSU in 2020, Health Science.

Allison Legare, PA-C

Allison Legare is a board-certified Physician Assistant who received her Masters of Physician Assistant Studies from the University of North Texas Health Science Center.

WHAT MAKES US DIFFERENT

At Texas Regional Asthma, Allergy & Immunology Center, your care is led by physicians who are fellowship-trained and board-certified in Allergy and Immunology—the highest level of specialization in diagnosing and treating allergic, asthmatic, and immune system disorders.

Find the Office that Best Fits Your Needs

Two Convenient Locations

  • 900 E Southlake Blvd
    Southlake, TX 76092

  • (817) 421-0770

  • (817) 421-4759

  • 3349 Golden Triangle Blvd
    Fort Worth, TX 76177

  • (817) 421-0770

  • (817) 562-5008

TESTIMONIALS

“Texas Regional Asthma & Allergy Center offers a modern approach that gets you to maintenance fast. The staff is professional and friendly and the team genuinely cares about your allergy management/health welfare. I’m so grateful that my primary physician highly recommended Dr. Leon for my severe allergies. It has been a positive and productive experience. I’m looking forward to enjoying an active life in Texas air.”

- Donyelle L.

“Dr Shakouri is amazing! Very thorough, attentive and genuinely cares for his patients. My health is starting to get better after 15 years of allergies and an immune deficiency disorder. I have not felt this healthy in a very long time.”

- Lori M.

“Texas Regional Asthma and Allergy Center provides excellent care. They are very responsive and proactive in the care and solutions offered to treat symptoms. I have been a patient with this clinic for many years and every doctor and PA I have seen is very compassionate and caring. I highly recommend them to everyone.”

- NH

“From check in to check out there is no wait time, an absolute seamless process. Dr. Leon is very thorough. He discovered all of my nasal problems and has brought me much relief. His nurse is very personable and professional. Thanks you everyone in the office for your absolute kindness.”

- Stacy R.

“I’ve been going to here for years. Dr. Shakhouri and Tiffany, his nurse, have always taken exceptional care of me. I couldn’t be at a better place!”

- Laurie S.